Left atrial appendage closure for stroke prevention in atrial fibrillation: response to an unmet need with an unclear direction.

نویسندگان

  • Darae Ko
  • Elaine M Hylek
چکیده

Five-Year Outcome of Catheter Ablation of Persistent Atrial Fibrillation Using Termination of Atrial Fibrillation as a Procedural Endpoint Daniel Scherr, MD; Paul Khairy, MD, PhD; Shinsuke Miyazaki, MD; Valerie Aurillac-Lavignolle, BSc; Patrizio Pascale, MD; Stephen B. Wilton, MD; Khaled Ramoul, MD; Yuki Komatsu, MD; Laurent Roten, MD; Amir Jadidi, MD; Nick Linton, MD, PhD; Michala Pedersen, MD; Matthew Daly, MD; Mark O’Neill, MD; Sebastien Knecht, MD, PhD; Rukshen Weerasooriya, MD; Thomas Rostock, MD; Martin Manninger, MD; Hubert Cochet, MD; Ashok J. Shah, MD; Sunthareth Yeim, MD; Arnaud Denis, MD; Nicolas Derval, MD; Meleze Hocini, MD; Frederic Sacher, MD; Michel Haissaguerre, MD; Pierre Jais, MD · · · · · · · · · · · · · · · · · · · · · · 18

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A Semi-Automated Algorithm for Segmentation of the Left Atrial Appendage Landing Zone: Application in Left Atrial Appendage Occlusion Procedures

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INTRODUCTION Stroke accounts for approx. 90% of thromboembolic complications associated with atrial fibrillation. The use of oral anticoagulants is the most effective therapy but is associated with risk of haemorrhagic complications. AIM In this article, we describe a series of patients with atrial fibrillation, cardiogenic stroke history, and contraindications for long-term anticoagulant the...

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Left Atrial Appendage Closure Under Intracardiac Echocardiographic Guidance: Feasibility and Comparison With Transesophageal Echocardiography

BACKGROUND Transcatheter left atrial appendage closure is an alternative therapy for stroke prevention in atrial fibrillation patients. These procedures are currently guided with transesophageal echocardiography and fluoroscopy in most centers. As intracardiac echocardiography (ICE) is commonly used in other catheter-based procedures, we sought to determine the safety and effectiveness of intra...

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Left Atrial Appendage Closure as an Alternative to Warfarin for Stroke Prevention in Atrial Fibrillation: A Patient-Level Meta-Analysis.

BACKGROUND The risk-benefit ratio of left atrial appendage closure (LAAC) versus systemic therapy (warfarin) for prevention of stroke, systemic embolism, and cardiovascular death in nonvalvular atrial fibrillation (NVAF) requires continued evaluation. OBJECTIVES This study sought to assess composite data regarding left atrial appendage closure (LAAC) in 2 randomized trials compared to warfari...

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Left atrial appendage closure: outcomes and challenges

Whereas the left atrial appendage plays a rather minor role under physiological circumstances, it gains an importance in patients with atrial fibrillation. Compelling evidence has revealed that the left atrial appendage is implicated as the source of thrombus in the vast majority of strokes in atrial fibrillation. Oral anticoagulation remains the standard of care for stroke prevention in atrial...

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عنوان ژورنال:
  • Circulation. Arrhythmia and electrophysiology

دوره 8 1  شماره 

صفحات  -

تاریخ انتشار 2015